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Delighted to host @resiapretorius and @PutrinoLab at Yale today. @ValterVSM and I learned how to image #microclots and activated platelets. Activated platelet stained with anti-CD62P antibody are evident just looking through the eyepiece 👀 This is from a #longCOVID patient👇🏽😭
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@cstroeckw Many thanks to you and other patient advocates, this pandemic has propelled me to investigate the pathobiology of #longCOVID, #MECFS and #longLyme 🙏🏼 If enough people do the same, we can change how society and medicine view post-acute infection syndromes.
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A very important and informative thread about why the Omicron XBB.1.5 subvariant is now dominating in the Northeast US and is expected to spread. Please protect yourselves and others by wearing N95 masks. I am truly concerned about the #longCOVID wave that follows this infection. twitter.com/yunlong_cao/st…
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We are looking for people who never had COVID or who recovered from COVID as important control participants in our Yale LISTEN study. Please sign up if you can help us understand the pathophysiology of #longCOVID and post-vaccine adverse events 🙏🏼
medicine.yale.edu/ycci/listen-st…
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A team member working on our #PrimeandSpike nasal spray COVID booster vaccine developed #longCOVID 😭
Long COVID is a global crisis affecting millions of lives. It is impacting our ability to do science, research and development.
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Very excited that our PaxLC clinical trial on #longCOVID patients is now open, led by @hmkyale! This is a phase 2, 1:1 randomized, double-blind, placebo-controlled research study in 100 non-hospitalized highly symptomatic long COVID. (1/)
clinicaltrials.gov/ct2/show/NCT05…
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We suspect that a subset of #longCOVID patients have viral reservoirs. The reason we use a 15-day trx (not a 5-day used for acute infection) is to allow the drug to eliminate the virus that is causing chronic infection and to remove such reservoirs. (4/)
nature.com/articles/s4159…
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We are now enrolling in the #PaxLCTrial; randomizing people with #longCOVID to 15 days of Paxlovid (nirmatrelvir/ritonavir) or placebo (placebo/ritonavir). Currently people in CT, NY, and FL can enroll. Hope to expand to other states soon. For more info 👉🏼 kindred.hugo.health/pax-lc
